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Amphetamine is understood to inhibit monoamine oxidase, Whilst the flexibility of amphetamine and its metabolites to inhibit various P450 isozymes as well as other enzymes has not been sufficiently elucidated. In vitro experiments with human microsomes point out slight inhibition of CYP2D6 by amphetamine and slight inhibition of CYP1A2, 2D6, and 3A